F.D.A. Will Remove Black Box Warnings From Hormone Treatments for Menopause

The benefits of hormone replacement have been underappreciated, Dr. Marty Makary, the agency’s commissioner, said on Monday. Critics described evidence for the change as insufficient.Estrogen pills used to treat menopause symptoms. Many hormone treatments have carried prominent warnings since 2003, when large trials found that oral combinations of estrogen and progestin raised the risks of blood clots and breast cancer.